Macronutrients—carbohydrates, fats, and proteins—are vital for body development, maintenance, disease prevention, metabolism, and overall health, especially during recovery. They serve as the body’s primary fuel source, providing calories needed for functioning. Adequate intake of macronutrients supports physical energy and mental health, improving nutritional status and treatment effectiveness, while reducing cravings and preventing substance use recurrence. Insufficient intake can lead to depression, anxiety, and low energy, potentially triggering substance use or relapse.